In silico search of Myrcia tomentosa (Myrtaceae) antineoplastic potential

Myrcia tomentosa, popularly known as “guava-brava”, belongs to the Myrtaceae family, widely used in folk medicine treat various diseases. There already are studies proving effectiveness of several its components. However, there few specific articles on biological potential M. tomentosa compounds. The aim this study was evaluate antineoplastic activity from tomentosa. For these, we performed silico analysis pharmacological and toxicological activities, besides interaction between molecules with human targets redocking analysis. Our results showed that α-cadinol highest score molecule 11 compounds present screening Among possible actions, cytochrome P450 19 A1 were found. This related breast cancer is main target drugs cancer’s treatment. Therefore, believe should be considered future vitro vivo assays against cancer.